The FHXB Friedrichshain-Kreuzberg Museum is a Berlin district museum and sees itself as a forum and moving memory of the district with its exhibition and event programme, collection, archive and mediation offerings. The museum's work focuses on social movements, urban development, industrial and migration history. A central concern of the museum's work is the addressing of previously underrepresented topics and perspectives. In doing so, the museum aims to focus on marginalised positions and to make the experience of people with experiences of discrimination visible.

Starting from a position of historical critique, the FHXB Museum has helped shape the critique of representation, the museum discourse on migration and postcolonial museology for several decades. The museum is involved in current social and political developments in the district and focuses on participatory project development.

In addition to changing exhibitions, the permanent exhibition in the glass tower tells the story of the protest movements and urban redevelopment in the former Kreuzberg SO 36 neighbourhood. In the participatory permanent exhibition "Local Histories – Distant Conversations – Local Chats", various places in the district can be explored through the voices and perspectives of residents and new Berliners. Printing presses and typesetting cabinets from the former publishing and printing district around Ritterstraße are on display in the historic museum print shop, where printing and bookbinding workshops for children, young people and adults also take place.